产品编号 | RC10062 |
说明书 | |
英文名称 | FSLLRY-NH2 |
CAS编号 | 41753-55-3 |
分子式 | C39H60N10O8 |
分子量 | 796.96 |
Sequence | Phe-Ser-Leu-Leu-Arg-Tyr-NH2 |
作用靶点 | Protease Activated Receptor (PAR) |
作用通路 | GPCR/G Protein |
储存方式 | Sealed storage, away from moisture and light Powder -20°C 1 year,In solvent : -80°C, 6 months; -20°C, 1 month (sealed) |
储存方式 | DMSO 中的溶解度: 100 mg/mL (125.48 mM; 超声助溶; 吸湿的DMSO 对产品的溶解度有显著 影响,请使用新开封的DMSO) |
生物活性 | FSLLRY-NH2 是蛋⽩酶激活受体2 (PAR2)抑制剂。 |
IC₅₀ & Target | PAR2 |
体内研究 | Treatment with FSLLRY-NH2 (50 μg per rat administered intranasally at 1 hour postresuscitation) significantly improves neurological outcome and reduces the number of degenerating hippocampal neurons after ACA (asphyxial CA). Report has not independently confirmed the accuracy of these methods. They are for reference only. |